Research & Studies

In this episode, Dr. Craig Koniver, M.D., a board-certified physician trained at Brown University and Thomas Jefferson University, discusses the therapeutic application of peptides and hormones for enhancing physical and mental health and performance. They explore GLP-1 analogs for weight loss, BPC-157 for wound healing and reducing inflammation, as well as peptides that increase growth hormone, improve REM sleep, and enhance cognitive function. They also cover testosterone therapy, NAD, NMN, and NR supplementation, methylene blue for mitochondrial health, stem cell therapies, and supplements such as CoEnzyme Q10 and methylated B vitamins.

Rachel Rubin is a board-certified urologist & one of the nation's foremost experts in sexual health. In this video, she shares her deep expertise on the topic of women’s sexual health, exploring why this area remains so neglected in traditional medicine & highlighting the critical differences in how men & women experience hormonal decline with age. Rachel explains the physiology of the menstrual cycle, the complex hormonal shifts of perimenopause, & the health risks associated with menopause, including osteoporosis, cardiovascular disease, dementia, & recurrent urinary tract infections. She discusses the controversy surrounding hormone replacement therapy (HRT) & provides guidance on the safe & personalized use of estrogen, progesterone, & testosterone in women.

In this interview with Dr. Matt Cook, a former anesthesiologist turned functional medicine pioneer, we uncover the revolutionary treatment pyramid that’s transforming how we approach longevity, from daily biohacking routines to stem cells and gene therapies. Could his three-tier approach be the key to extending not just lifespan, but health span? Watch to find out why some of the world’s top health experts are calling this the future of medicine!

Dr. Gottfried, a Harvard-educated physician and a leading voice in hormone health advice, shares her expert insights on how to fix PCOS, improve fertility hormones, and increase your chance of pregnancy. Discover the secrets to balancing your hormones naturally, understand the risks associated with PCOS, and learn how to become more fertile with practical and science-backed strategies. Dr. Gottfried explains the complexities of PCOS, offering clarity on how do I know if I have PCOS and providing actionable tips for managing this condition. From autoimmune conditions to enhancing your fertility hormones, this episode covers everything you need to know about optimizing woman hormone health.

Dr. David Sinclair, tenured Professor of Genetics at Harvard Medical School and an expert researcher in the field of longevity. In this interview, Dr. Huberman and Sinclair discuss the cellular and molecular mechanisms of aging and what we all can do to slow or reverse the aging process. They discuss fasting and supplementation with resveratrol, NAD, metformin, and NMN. They also discuss the use of caffeine, exercise, cold exposure, and why excessive iron load is bad for us. They discuss food choices for offsetting aging and promoting autophagy (clearance of dead cells) and the key blood markers everyone should monitor to determine your biological versus chronological age. This episode includes lots of basic science and specific, actionable protocols, right down to the details of what to do and when.

What are peptides? In this episode Joy Kong, M.D. and UCLA-trained, triple board-certified physician discusses how to use peptides to optimize your wellness. She specializes in stem cell therapy, ketamine therapy, as well as a wide range of therapeutic modalities to enhance overall health and combat diseases in a holistic approach, esp. By enhancing the body’s innate regenerative potentials. The peptides covered in this video include: BPC 157 TB 500 (Thymosin beta 4 or TB4), TA1 (thymosin alpha 1), Epitalon, Dohexa, Cerebrolysin, Selank Semax, PE-22-28, Ipramorelin, CJC 1295 Tesamorelin, MOTS-c Semaglutide, 5-amino-1-MQ, Melanotan, LL37, PT 141, and GHK-Cu.

In this episode Dr. Huberman sat down with Sara Gottfried, M.D., a Harvard-trained, board-certified gynecologist. Dr. Gottfried specializes in hormone health, vitality and longevity using precision/personalized approaches. Here they discuss female hormone health, puberty, perimenopause, and menopause, hormone testing, the microbiome, stress related hormone challenges, their causes, and various treatments. They also discuss fertility, birth control and tools for improving microbiome health, treating PCOS, insulin management, and nutrition, supplementation, and exercise programs for women. While the episode focuses mainly on female hormones, males will also benefit from the discussion because it includes actionable tools suggested for managing stress, bolstering the gut microbiome, and boosting our immunity.

Is alcohol truly harmless—or have we been sold a lie? In this eye-opening conversation, Dr. Kelly Casperson is joined by James Swanwick to expose the real effects of alcohol on your brain, body, and relationships. From dopamine to dementia, cultural myths to mental clarity—this episode dives deep into the science and societal conditioning around alcohol, outlining healthy ways to let loose, and redefining what it means to live a life less dependent on alcohol without the expectations of sobriety.